Robust and Fast Whole Brain Mapping of the RF Transmit Field B1 at 7T

نویسندگان

  • Antoine Lutti
  • Joerg Stadler
  • Oliver Josephs
  • Christian Windischberger
  • Oliver Speck
  • Johannes Bernarding
  • Chloe Hutton
  • Nikolaus Weiskopf
چکیده

In-vivo whole brain mapping of the radio frequency transmit field B(1) (+) is a key aspect of recent method developments in ultra high field MRI. We present an optimized method for fast and robust in-vivo whole-brain B(1) (+) mapping at 7T. The method is based on the acquisition of stimulated and spin echo 3D EPI images and was originally developed at 3T. We further optimized the method for use at 7T. Our optimization significantly improved the robustness of the method against large B(1) (+) deviations and off-resonance effects present at 7T. The mean accuracy and precision of the optimized method across the brain was high with a bias less than 2.6 percent unit (p.u.) and random error less than 0.7 p.u. respectively.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fast and Robust B1 Mapping at 7T by the Bloch-Siegert Method

Introduction: B1 mapping has a variety of applications including the design of RF pulses in parallel transmit systems, and flip angle calibration for T1 mapping. Many existing B1 mapping methods suffer from T1 dependence, long scan time or inability to handle the large B1 inhomogeneity that occurs even across the human brain at 7T. The Bloch-Siegert B1 mapping method has been recently introduce...

متن کامل

Correction of Rf Inhomogeneities in Flash-based T1 Mapping Using Unified Segmentation

Introduction: Quantitative T1 mapping based on 3D FLASH acquisitions with variable excitation flip angles (VFA) is fast and robust (1, 2). However, high accuracy can only be achieved when the local flip angle is known precisely (1). At higher static magnetic fields local flip angles may deviate considerably from the nominal flip angle due to inhomogeneities of the RF transmit/B1 field (3, 4). T...

متن کامل

Magnetic resonance spectroscopic imaging using parallel transmission at 7T

Conventional magnetic resonance spectroscopic imaging (MRSI), also known as phase-encoded (PE) chemical shift imaging (CSI), suffers from both low signal-to-noise ratio (SNR) of the brain metabolites, as well as inflexible tradeoffs between acquisition time and spatial resolution. In addition, although CSI at higher main field strengths, e.g. 7 Tesla (T), offers improved SNR over clinical 1.5T ...

متن کامل

Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT)

Quantitative mapping of the longitudinal relaxation rate (R1=1/T1) in the human brain enables the investigation of tissue microstructure and macroscopic morphology which are becoming increasingly important for clinical and neuroimaging applications. R1 maps are now commonly estimated from two fast high-resolution 3D FLASH acquisitions with variable excitation flip angles, because this approach ...

متن کامل

T1 contrast in the human brain at 7 Tesla

Introduction: MRI in humans at ultra-high field offers not only high baseline sensitivity but also interesting contrast behavior. Compared to lower field strength T1 relaxation times generally increase but seem to remain highly diverse, promising strong T1 contrast especially in brain imaging. Exploring this potential is mainly hampered by the non-uniformity of the transmit RF fields generate b...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2012